Selected Publications


Cabarca S, Frazão de Souza M, Albert de Oliveira A, Vignoli Muniz GS, Lamy MT, Vinicius Dos Reis C, Takarada J, Effer B, Souza LS, Iriarte de la Torre L, Couñago R, Pinto Oliveira CL, Balan A. Structure of the Mycobacterium tuberculosis cPknF and conformational changes induced in forkhead-associated regulatory domains. Curr Res Struct Biol. 2021 Jul 23;3:165-178. doi: 10.1016/j.crstbi.2021.07.001

De la Torre, LI; Vergara Mesa, JG; Cabarca, S; Costa Martins, AG; Balan, A.  Comparison of the Carbohydrate transporters in Mycobacterium tuberculosis. BMC Genomics, BMC Genomics. 2021 Nov 19;22(1):841. doi: 10.1186/s12864-021-07972-w

Oliveira, MCB e Balan, A. The ATP-Binding Cassette (ABC) Transport Systems in Mycobacterium tuberculosis: Structure, Function, and Possible Targets for Therapeutics. BIOLOGY, v. 9, p. 443-463, 2020.

Cremonesi, AS; De la Torre, LI; Souza, MF; Muniz, GVS; Lamy, M Tereza; Oliveira, CLP; Balan, A. The citrus plant pathogen Xanthomonas citri has a dual polyamine-binding protein. Biochem Biophys Rep. 2021 Nov 16;28:101171. doi: 10.1016/j.bbrep.2021.101171.

Vignoli, GS, De La Torre, LI, Duarte EL, Lorenzon EN, Cilli EM, Balan A, Lamy, MTeresa. Interaction of synthetic antimicrobial peptides of the Hylin a1 family with models of eukaryotic structures: Zwitterionic membranes and DNA. Biochemistry and Biophysics Reports, Vol 24, 2020, 100827. 

Guerra G, Balan A. Genetic and structural determinants on iron assimilation pathways in the plant pathogen Xanthomonas citri subsp. citri and Xanthomonas sp. Braz J. Microbiol. DOI 10.1007/s42770-019-00207-x, 2019.

Cerone AN, Cambui CP, Moreno AC, Fessel MR, Balan A. Mycobacterium tuberculosis CysA2 is a dual sulfurtransferase with activity against thiosulfate and 3-mercaptopyruvate and interacts with mammalian cells. Scientific Reports, 9:16791, 2019.

Sampaio A, Pegos VR, Oshiro EE, Balan A. The periplasmic binding protein NrtT affects xantham gum production and pathogenesis in Xanthomonas citri. FEBS Open Bio. 7:1499-1514, 2017.

Pereira CT, Roesler C, Faria JN, Fessel MR, Balan A. Sulfate-Binding Protein (Sbp) from Xanthomonas citri: Structure and Functional Insights. Mol Plant Microbe Interact. 30: 578-588, 2017.

Pereira MR, Maester TC, Mercaldi GF, de Macedo Lemos EG, Hyvonen M, Balan A. From a Metagenomic Source to a High-Resolution Structure of a Novel Alkaline Esterase. Applied Microbiology and Biotechnology, 101: 4935-4949, 2017.

Pegos VR, Santos RML, Medrano FJ, Balan A. Structural features of PhoX, one of the phosphate-binding proteins from Pho regulon of Xanthomonas citri. PLoS One. 22;12(5):e0178162, 2017.

Maester TC, Pereira MR, Mercaldi GF, Balan A, de Macedo Lemos EG. Characterization of EST3: A metagenome-derived esterase with potential for bioremediation application. Applied Biotechnology and Microbiology. 10.1007/s00253-016-7385-z. 2016.

Ferreira EL, Batista MT, Cavalcante RC, Pegos VR, Passos HM, da Silva DA, Balan A, Ferreira LC, Ferreira RC. Sublingual immunization with the phosphate binding-protein (PstS) reduces oral colonization by Streptococcus mutans. Mol Oral Microbiol. doi: 10.1111/omi.12142, 2015.

Pereira MR, Mercaldi GF, Maester TC, Balan A, de Macedo Lemos EG. Est16, a New Esterase Isolated from a Metagenomic Library of a Microbial Consortium Specializing in Diesel Oil Degradation. PLoS One. 10(7):e0133723. doi: 10.1371/journal.pone.0133723, 2015.

Pereira CT, Moutran A, Fessel M, Balan A. The sulfur/sulfonates transport systems in Xanthomonas citri pv. citri. BMC Genomics. 16(1):524. doi: 10.1186/s12864-015-1736-5, 2015.

Kuniyoshi TM, Balan A, Schenberg AC, Severino D, Hallenbeck PC. Heterologous expression of proteorhodopsin enhances H2 production in Escherichia coli when endogenous Hyd-4 is overexpressed. J Biotechnol. 20;206:52-7. doi: 10.1016/j.jbiotec.2015.04.009, 2015.

Pegos, V.R.; Canevarolo, R.R.; Sampaio, A.P.; Balan, A.; Zeri, A.C. Xanthan Gum Removal for 1H-NMR Analysis of the Intracellular metabolome of the bacterium Xanthomonas axonopodis pv. citri 306. Metabolites, 4: 218-231, 2014.

Pegos, V.R.; Nascimento, J.F.; Sobreira, T.J.; Pauletti, B.A.; Paes-Leme, A.; Balan, A. Phosphate regulated proteins of Xanthomonas citri subsp. citri: a proteomic approach. J. Proteomics, 108: 78-88, 2014.

Medrano F.J.; de Souza, C.S.; Romero, A.; Balan, A. Structure determination of a sugar-binding protein from the phytopathogenic bacterium Xanthomonas citri. Acta Cryst. F Struct. Biol. Com., 70: 564-571, 2014.

Tofoli, F.; Bolanos, V.; Sanches, M.; Barbosa, J.A.R.G.; Benedetti, C.E.; Blundell, T. L.; Balan, A; Structural and physiological analyses of the alkanesulphonate-binding protein (SsuA) of the citrus pathogen Xanthomonas citri. PloS One, 8: e80083, 2013.

Santacruz-Perez, C; Pegos, V.R.; Barbosa, J.A.R.G.; Balan, A. A specific interdomain interaction preserves the structural and binding properties of the ModA protein from the phytopathogen Xanthomonas citri – domain interaction and transport in ModA. Arch. Biochem. Biophys., 539: 20-30, 2013.

Porchia, BFMM; Diniz, M; Cariri, FAMO; Balan, A; Braga, CJM; Fereira, LCS. Purified herpes simplex type 1 glycoprotein D (gD) genetically fused with the type 16 human papillomavirus E7 oncoprotein enhances antigen-specific CD8+ T cell responses and confers protective anti-tumor immunity. Molecular Pharmaceuticals, 8: 2320-2330, 2011.

Marengo, E.B.; Balan, A.; Robson Lopes Melo; Tamborugi, D.V.; Rizzo, L.V.; Sant’AnnaA, O.A. Mycobacterium leprae Hsp65 mutant as a candidate for mitigating lupus aggravation in mice. PLoS One. 6(9):e24093, 2011.

Rodrigues, J.F.; Mathias-Santos, C.; Sbrogio-Almeida, M.E.; Cabrera-Crespo, J.; Amorin, J.H.; Balan, A., Ferreira, L.C.S. Heat-labile toxins produced by enterotoxigenic Escherichia coli strains derived from human or swine hosts show differences in toxicity and adjuvant effects. J Biol Chem. 286: 5222-33, 2011.

Álvares-Flores, Ramos, OHP, Konno, Balan A, K, Chudzinski-Tavassi, AM. Losac: Firts hemolin that exhibits procoagulant activity through selective factor X proteolytic activation. J Biol Chem. 286: 6918-6928, 2011.

Menezes, M., Oliveira, A.K., Melo, L., Lopes-Ferreira, M, Rioli, V., Balan, A., Leme, AFP, Serrano, SMT.Disintegrin-like/cysteine-rich domains of the reprolysin HF3: site-directed mutagenesis reveals essential role of specific residues. Biochimie. 93: 345-351, 2011.

Amorim, J.H., Porchia, B.F.M.M., Balan, A., Cavalcante, R.C.M., da Costa, S.M., de Barcelos, A.M.A., de Souza, L.C.F. Refolded dengue virus type 2 NS1 protein expressed in Escherichia coli preserves structural and immunological properties of the native protein. Journal of Virological Methods. , p.16 – 22, 2010.

Souza, C.S., Ferreira, L.C.S., Thomas, L., Barbosa, J.A.R.G., Balan, A. Crystallization, data collection and processing of the phytopathogen Xanthomonas axonopodis pv citri Maltose-Binding Protein (MalE). Acta Crystallographica. Series F. , 65: 105 – 107, 2009.

Balan, A., Perez, C.S., Moutran, A., Ferreira, L.C.S.F., Neshich, G., Barbosa, Joao A. Crystallographic structure and substrate-binding interactions of the molybdate-binding protein of the phytopathogen Xanthomonas axonopodis pv. citri. Biochimica et Biophysica Acta. Protein Structure and Molecular Enzymology. 1784: 393 – 399, 2008.

Lasaro, MA, J.F. Rodrigues, Mathias-Santos, C., Guth, B.E.C., Balan, A., Sbrogio-Almeida, M.E., Ferreira, L.C.S. Genetic diversity of heat-labile toxin expressed by enterotoxigenic Escherichia coli strains isolated from humans. Journal of Bacteriology. 190: 2400 – 2410, 2008.

Balan, A., Souza, C.S., Ferreira, R.C.S., Ferreira, L.C.S. Production of the Refolded Oligopeptide-Binding Protein (OppA) Encoded by the Citrus Pathogen Xanthomonas axonopodis pv. citri for Structural Analysis. Genetics and Molecular Research. 12: 233 – 239, 2008.

Nepomuceno, R.; Tavares, M.; Balan, A.; Ribeiro, J.; Guimarães, K.; Cai, S.; Ferreira, L.C.S.; Ferreira, R.C.C. The oligopetide binding protein (OppA) of Streptococcus mutans. Oral Microbiology and Immunology 22: 277-184, 2007.

Nakamatsu, E.H.; Fijihira, E.; Ferreira, R.C.C.; Balan, A.; Costa, S.O.P. and Ferreira, L.C.S. The oligopeptide uptake system and aminoglycoside sensitivity in Escherichia coli K12. FEMS Microbiology Letters, 269: 229-233, 2007.

Balan, A.; Santacruz, C.P.; Moutran, A.; Ferreira, R.C.; Medrano, F.J.; Perez, C.A.; Ramos, C.H.; Ferreira, L.C. The molybdate-binding protein (ModA) of the plant pathogen Xanthomonas axonopodis pv. citri. Protein Expression and Purification, 50: 215-222, 2006.

Santacruz, C.P.; Balan, A.; Ferreira, L.C.; Barbosa, J.A. Crystallization, data collection and phasing of the molybdate-binding protein of the phytopathogen Xanthomonas axonopodis pv. citri. Acta Crystallographyca Section F Struct. Biol. Cryst. Commun., 62: 289-91. 2006.